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M-CSF, Human(CHO-expressed) Europäischer Partner

ArtNr Z02924-10
Hersteller GenScript
Menge 10 ug
Quantity options 1 mg 10 ug 50 ug
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Sequence Glu33-Ser190 (Accession # NP_757350).
Citations 1. Fiona J. Pixley and E. Richard Stanley (2004), Trends in Cell Biology, 14: 628. 2. Kauma SW et al. (1991), J Clin Endocrinol Metab, 73(4), 746. 3. Jani R. Jensen et al. (2010), Fertil Steril. 93(1): 251. 4. Baiocchi G et al. (1991), Cancer, 1991, 67:990.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias protein/Z02924_10-Macrophage_Colony_Stimulating_Factor_M_CSF_Human,Human Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages[1]. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells[2]. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers, [1][3][4] .</td></tr><tr><th>M.W.</th><td colspan="7"> 32-40 kDa, observed by non-reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% as analyzed by SDS-PAGE and HPLC.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> <0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50, 2×105 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, human Macrophage-Colony Stimulating Factor (rhM-CSF), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhM-CSF should be stable up to 1 week at 4C or up to 2 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O or PBS at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Glu33-Ser190 (Accession
Similar products Macrophage
Versandbedingung Gekühlt
Lieferbar
Specificity ED50, 2x105 units/mg.
Manufacturer - Category
Proteins
Country of Origin
USA
Shipping Temperature
4°C
Storage Conditions
-80°C
Molecular Weight
32-40 kDa, observed by non-reducing SDS-PAGE.
Product Line
Growth Factors
Manufacturer - Specificity
ED50, 2x105 units/mg.
Description
Human Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages[1]. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells[2]. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers, [1][3][4] .
Reconstitution
Reconstituted in ddH2O or PBS at 100 ug/ml.
Formulation
Lyophilized after extensive dialysis against PBS.
Endotoxin Level
<0.2 EU/ug, determined by LAL method.
Notes
For research use only

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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