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UBE2K/E2-25K, His, Human

UBE2K/E2-25K, His, Human

Hersteller	GenScript
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Neural Adhesion Molecules By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Autophagy Cardiovascular Research Ischemia & Reperfusion Injury By Organ Bladder Cancer
Typ	Proteins
Specific against	Human
Format	Sterile Filtered White lyophilized (freeze-dried) powder.
Menge	50ug
ArtNr	Z02966-50
Targets	CD324, HTT
eClass 6.1	34160400
eClass 9.0	42020190
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Description	Ubiquitin-conjugating enzyme E2 K is a protein that in humans is encoded by the UBE2K gene. The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.
Endotoxin Level	Less than 1EU/ug of rHuUBE2K, His as determined by LAL method.
Formulation	Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
M.W.	Approximately 23.4 kDa, a single non-glycosylated polypeptide chain containing 200 amino acids (a.a.) of human UBE2K and 8 a.a. vector sequence including 6 x His tag at N-terminus.
Product Line	Others
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <=-20C. Further dilutions should be made in appropriate buffered solutions.
Storage	This lyophilized preparation is stable at 2-8C, but should be kept at -20C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -70C. Avoid repeated freeze/thaw cycles.
Product Origin	USA

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