G-CSF, Human

Hersteller GenScript
Kategorie
Typ Proteins
Specific against Human
Menge 1mg 
ArtNr Z02974-1
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Product Line
Cytokine, Chemokines & Growth Factors
Description
Granulocyte Colony-Stimulating Factor (G-CSF), contains internal disulfide bonds. Among the family of colony-stimulating factors, Granulocyte Colony Stimulating Factor (G-CSF) is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of Granulocyte Colony Stimulating Factor (G-CSF) can be induced by bacterial endotoxins, TNF, Interleukin-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of Granulocyte Colony Stimulating Factor (G-CSF). In epithelial, endothelial, and fibroblastic cells secretion of Granulocyte Colony Stimulating Factor (G-CSF) is induced by Interleukin-17. Recombinant, human Granulocyte Colony-Stimulating Factor (rhG-CSF), produced in E. coliis a single non-glycosylated polypeptide chain containing 175amino acids. A fully biologically active molecule, rhG-CSF is obtained by proprietary chromatographic techniques at GenScript, with an apparent molecular mass of 18.8kDa analyzed by reducing SDS-PAGE.
M.W.
18.8kDa, observed by reducing SDS-PAGE.
Purity
> 95% by SDS-PAGE and HPLC analyses.
Endotoxin Level
<0.2 EU/ug, determined by LAL method.
Specific Activity
ED50, 1.0x 107 IU/mg.
Storage
Lyophilized recombinant, human Granulocyte Colony-Stimulating Factor (rhG-CSF), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhG-CSF should be stable up to 2 weeks at 4C or up to 3 months at -20C.
Formulation
Lyophilized after extensive dialysis against 25mM Tris, pH8.0.
Reconstitution
Reconstituted in ddH2O at 100 ug/ml.
Sequence
Thr27-Pro200 (accession number:Q8N4W3), expressed with an N-terminal Met.
Note
For research use only
Menge: 1mg 
Lieferbar: In stock
Listenpreis: 1.634,60 €
Preis: 1.634,60 €
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