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IL-1β, Human(CHO-expressed) Europäischer Partner

ArtNr Z02978-50
Hersteller GenScript
Menge 50 ug
Quantity options 1 mg 10 ug 50 ug
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Sequence Ala117-Ser269 (Accession # NP_000567).
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias protein/Z02978_50-Interleukin_1_beta_IL_1_beta_Human,Interleukin 1 beta, is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine.</td></tr><tr><th>M.W.</th><td colspan="7"> 17kDa, observed by non-reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% as analyzed by SDS-PAGE and HPLC.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> <0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50 1 x 108 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, human Interleukin 1 beta (IL-1 beta), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhIL-1beta should be stable up to 1 week at 4C or up to 2 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O or PBS at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Ala117-Ser269 (Accession
Similar products Interleukin-1
Versandbedingung Gekühlt
Lieferbar
Specificity ED50 1 x 108 units/mg.
Manufacturer - Category
Proteins
Country of Origin
USA
Shipping Temperature
4°C
Storage Conditions
-80°C
Molecular Weight
17kDa, observed by non-reducing SDS-PAGE.
Product Line
Cytokines
Manufacturer - Specificity
ED50 1 x 108 units/mg.
Description
Interleukin 1 beta, is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine.
Reconstitution
Reconstituted in ddH2O or PBS at 100 ug/ml.
Formulation
Lyophilized after extensive dialysis against PBS.
Endotoxin Level
<0.2 EU/ug, determined by LAL method.
Notes
For research use only

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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