| Description |
Interleukin 1 beta, is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine. |
| Storage |
Lyophilized recombinant, human Interleukin 1 beta (IL-1 beta), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhIL-1beta should be stable up to 1 week at 4C or up to 2 months at -20C. |
