|
Hersteller |
GenScript
|
|
Kategorie |
|
|
Typ |
Proteins |
|
Specific against |
Human |
|
Menge |
50.0ug |
|
ArtNr |
Z02981-50 |
|
eClass 6.1 |
34160400 |
|
eClass 9.0 |
42020190 |
|
Lieferbar |
 |
| Product Line |
Cytokine, Chemokines & Growth Factors |
| Description |
Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release. Recombinant Human IL-5, is homodimeric protein with molecular weight ranging from 29 to 35 kDa due to glycosylation. |
| M.W. |
ca.29-35 kDa, observed by non-reducing SDS-PAGE. |
| Purity |
> 95% as analyzed by SDS-PAGE and HPLC. |
| Endotoxin Level |
< 0.2 EU/ug, determined by LAL method. |
| Specific Activity |
ED50, 1x106 units/mg. |
| Storage |
Lyophilized recombinant, human Interlerkin 5 (rhIL-5), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhIL-5 should be stable up to 1 week at 4C or up to 2 months at -20C. |
| Formulation |
Lyophilized after extensive dialysis against PBS. |
| Reconstitution |
Reconstituted in ddH2O or PBS at 100 ug/ml. |
| Sequence |
I20-S134 (Accession # P05113). |
| Note |
For research use only |
