Hersteller |
GenScript |
Kategorie |
|
Typ |
Proteins |
Specific against |
Human |
Menge |
50ug |
ArtNr |
Z02981-50 |
Eclass 6.1 |
34160400 |
Eclass 9.0 |
42020190 |
Lieferbar |
|
Product Line |
Cytokine, Chemokines & Growth Factors |
Description |
Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release. Recombinant Human IL-5, is homodimeric protein with molecular weight ranging from 29 to 35 kDa due to glycosylation. |
M.W. |
ca.29-35 kDa, observed by non-reducing SDS-PAGE. |
Purity |
> 95% as analyzed by SDS-PAGE and HPLC. |
Endotoxin Level |
< 0.2 EU/ug, determined by LAL method. |
Specific Activity |
ED50, 1x106 units/mg. |
Storage |
Lyophilized recombinant, human Interlerkin 5 (rhIL-5), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhIL-5 should be stable up to 1 week at 4C or up to 2 months at -20C. |
Formulation |
Lyophilized after extensive dialysis against PBS. |
Reconstitution |
Reconstituted in ddH2O or PBS at 100 ug/ml. |
Sequence |
I20-S134 (Accession # P05113). |
Note |
For research use only |