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IFN-α 2b, Human Europäischer Partner

ArtNr Z03002-50
Hersteller GenScript
Menge 50 ug
Quantity options 1 mg 10 ug 50 ug
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Purity > 95% by SDS-PAGE and HPLC analyses.
Sequence Cys24-Glu188(Lys46Arg) (accession number: P01563).
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias protein/Z03002_50-Interferon_Alpha_2b_IFN_Alpha_2b_Human,Interferon-Alpha 2b (IFN-Alpha 2b), produced by leukocytes is a member of Interferon family. IFN-alpha is mainly involved in innate immune response against a broad range of viral infections. IFN-alpha 2 has three acid stable forms (a,b,c) signaling through IFNAR2. IFN-alpha 2b shares 99.4% aa sequence identity with both IFN-alpha 2a and 2c. IFN-alpha contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. Recombinant, human Interferon-Alpha 2b (rhIFN-Alpha 2b), produced in, E.coli, is a single non-glycosylated polypeptide chain containing 165 amino acids. A fully biologically active molecule, rhIFN-Alpha 2b has a molecular mass of 19.2kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.</td></tr><tr><th>M.W.</th><td colspan="7"> 19.2kDa, observed by reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7">> 95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> < 0.2 EU/ug, determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50, 2.0× 107 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, human Interferon-Alpha 2b (rhIFN-Alpha 2b), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhIFN-Alpha 2b should be stable up to 2 weeks at 4C or up to 3 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Cys24-Glu188(Lys46Arg) (accession number: P01563).</td></tr><tr><th>Note</th><td colspan="7"> For research use only</td></tr>
Similar products Interferon-Alpha
Versandbedingung Gekühlt
Lieferbar
Specificity ED50, 2.0x 107 units/mg.
Manufacturer - Category
Proteins
Country of Origin
USA
Shipping Temperature
4°C
Storage Conditions
-80°C
Molecular Weight
19.2kDa, observed by reducing SDS-PAGE.
Product Line
Cytokines
Manufacturer - Specificity
ED50, 2.0x 107 units/mg.
Description
Interferon-Alpha 2b (IFN-Alpha 2b), produced by leukocytes is a member of Interferon family. IFN-alpha is mainly involved in innate immune response against a broad range of viral infections. IFN-alpha 2 has three acid stable forms (a, b, c) signaling through IFNAR2. IFN-alpha 2b shares 99.4% aa sequence identity with both IFN-alpha 2a and 2c. IFN-alpha contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. Recombinant, human Interferon-Alpha 2b (rhIFN-Alpha 2b), produced in, E.coli, is a single non-glycosylated polypeptide chain containing 165 amino acids. A fully biologically active molecule, rhIFN-Alpha 2b has a molecular mass of 19.2kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Reconstitution
Reconstituted in ddH2O at 100 ug/ml.
Formulation
Lyophilized after extensive dialysis against PBS.
Endotoxin Level
< 0.2 EU/ug, determined by LAL method.
Notes
For research use only

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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