IL-5, Human

ArtNr	Z03007-10
Hersteller	GenScript
Menge	10 ug
Quantity options	1 mg 10 ug 50 ug
Kategorie	Oncology Food Safety Histamines Neuroscience Neuroinflammation Metabolism Diabetes Molecular Targets for Neuroscience Aging & Neurological Disorders By Cell Type Hematology Leukemia Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Cell Status Cell Metabolism Oxidative Stress By Organ Heart & Blood Cancer Bone Cancer
Typ	Proteins
Specific against	Human (Homo sapiens)
Purity	> 95% by SDS-PAGE and HPLC analyses.
Sequence	Ile20-Ser134 (accession number: P05113), expressed with an N-terminal Met.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	protein/Z03007_10-Interleukin_5_IL_5_Human,Interleukin-5 (IL-5) , produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release. Recombinant, Human Interleukin-5 (rhIL-5), produced in, E. coli, is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 116 amino acids each. A fully biologically active molecule, rhIL-5 has a molecular mass of 26.5 kDa analyzed by non-reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.</td></tr><tr><th>M.W.</th><td colspan="7"> 26.5 kDa, observed by non-reducing SDS-PAGE.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> < 0.2 EU/ug, determined by LAL method. </td></tr><tr><th>Specific Activity</th><td colspan="7"> ED50, 1.0× 106 units/mg.</td></tr><tr><th>Storage</th><td colspan="7"> Lyophilized recombinant, Human Interleukin-5 (rhIL-5), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rhIL-5 should be stable up to 2 weeks at 4C or up to 3 months at -20C.</td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized after extensive dialysis against PBS.</td></tr><tr><th>Reconstitution</th><td colspan="7"> Reconstituted in ddH2O at 100 ug/ml.</td></tr><tr><th>Sequence</th><td colspan="7"> Ile20-Ser134 (accession number: P05113), expressed with an N-terminal Met.</td></tr><tr><th>Note</th><td colspan="7"> For research use only</td></tr>
Similar products	Interleukin-5
Versandbedingung	Gekühlt
Lieferbar
Specificity	ED50, 1.0x 106 units/mg.
Manufacturer - Category	Proteins
Country of Origin	USA
Shipping Temperature	4°C
Storage Conditions	-80°C
Molecular Weight	26.5 kDa, observed by non-reducing SDS-PAGE.
Product Line	Cytokines
Manufacturer - Specificity	ED50, 1.0x 106 units/mg.
Description	Interleukin-5 (IL-5) , produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release. Recombinant, Human Interleukin-5 (rhIL-5), produced in, E. coli, is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 116 amino acids each. A fully biologically active molecule, rhIL-5 has a molecular mass of 26.5 kDa analyzed by non-reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Reconstitution	Reconstituted in ddH2O at 100 ug/ml.
Formulation	Lyophilized after extensive dialysis against PBS.
Endotoxin Level	< 0.2 EU/ug, determined by LAL method.
Notes	For research use only

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Z03007-10.pdf

Z03007-10-datasheet.pdf

Z03007-10-safety-datasheet.pdf