S100 calcium-binding protein A8 (S100A8), His, Human

Hersteller GenScript
Kategorie Produkte / Proteins
Typ Proteins
Specific against Human
Menge 50ug
ArtNr Z03088-50
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Description
S100 calcium-binding protein A8 (S100A8) is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A8 protein plays an important role in the regulation of inflammation. It can activate inflammatory cells and cytokines via chemotactic activity for neutrophils, and it can bind to the receptor for advanced glycation end products (RAGE) and Toll-like receptor 4 (TLR4), thus mediating intracellular inflammatory signaling transduction. S100A8 is detected in various human cancers, presenting abundant expression in neoplastic tumor cells as well as infiltrating immune cells. S100A8 exhibits high constitutive expression in neutrophils and activated macrophages, and is also found in epithelial cells under pathological conditions.
Recombinant S100 calcium-binding protein A8 (S100A8) with His tag produced in E. coli is a single chain containing 100 amino acids with molecular mass of 11.8 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
Product Line
PL311_Other Proteins
Storage Temperature
-65
Shipping Temperature
4
Menge: 50ug
Lieferbar: In stock
Listenpreis: 240,84 €
Preis: 240,84 €
lieferbar

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