Interleukin-5 Receptor Alpha, Human

Hersteller GenScript
Kategorie
Typ Proteins
Specific against Human
Menge 1mg
ArtNr Z03126-1
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Description
Interleukin-5 Receptor Alpha (IL-5RA), also known as CD125, belongs to the Type 5 subfamily in the type I cytokine receptor family. It is composed of a ligand-specific alpha subunit and a signal-transducing beta subunit shared by the receptors for IL-3 and GM-CSF. IL-5RA is mainly expressed on eosinophils and basophils, and plays important roles in the immunobiology of these cell types. It is reported that when stimulated by IL-5, eosinophils down-regulate surface IL-5RA expression to attenuate their IL-5 responsiveness. Elevated IL-5 production may induce immune cell infiltration which leads to allergic inflammation. IL-5RA has also been reported to promote the differentiation of basophils and B cells.
Product Line
PL307_Cytokines, Chemokines & Growth Factors
Storage Temperature
-65
Shipping Temperature
4
Menge: 1mg
Lieferbar: In stock
Listenpreis: 3.672,00 €
Preis: 3.672,00 €
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