Proheparin-binding EGF-like Growth Factor (HB-EGF), Human

Hersteller GenScript
Kategorie
Typ Proteins
Specific against Human
Menge 5ug
ArtNr Z03142-5
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Proheparin-binding EGF-like growth factor (HB-EGF), also known as DTR, DTS and HEGFL, is a member of the EGF family of mitogens. It is expressed in macrophages, monocytes, endothelial cells and muscle cells. HB-EGF signals through the EGF receptor to stimulate the proliferation of smooth muscle cells, epithelial cells and keratinocytes. Compared to EGF, HB-EGF binds the EGF receptor with higher affinity and is thus more mitogenic, probably due to its ability to bind to heparin and heparin sulfate proteoglycans. HB-EGF has been reported to act as a diphtheria toxin receptor, mediating endocytosis of the bound toxin.
Product Line
PL307_Cytokines, Chemokines & Growth Factors
Storage Temperature
-65
Shipping Temperature
4
Menge: 5ug
Lieferbar: In stock
Listenpreis: 30,10 €
Preis: 30,10 €
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