Fibroblast Growth Factor 8f(FGF-8f), Human

Hersteller GenScript
Kategorie
Typ Proteins
Specific against Human
Menge 10ug
ArtNr Z03203-10
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Fibroblast Growth Factor 8f (FGF-8f) is a cytokine belonging to the heparin-binding FGF family, which has at least 23 members. FGF-8 has 8 different isoforms, named FGF-8a through FGF-8h. Different FGF-8 isoforms have different receptor affinities, and thus participate in different signaling cascade pathways. FGF-8 has widespread expression during embryonic development, promoting gastrulation, somitogenesis, morphogenesis, and limb formation. FGF-8 also has oncogenic potential. While in normal cells FGF-8 is expressed at very low levels, in breast, prostate and ovarian cancer FGF-8 is highly expressed.FGF-8 promotes tumor angiogenesis by increasing neovascularization, and inducing osteoblastic differentiation.
Recombinant human Fibroblast Growth Factor 8f (rhFGF-8f) produced in E. coli is a single non-glycosylated polypeptide chain containing 223 amino acids. A fully biologically active molecule, rhFGF-8f has a molecular mass of 25.5 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
Product Line
PL307_Cytokines, Chemokines & Growth Factors
Storage Temperature
-65
Shipping Temperature
4
Menge: 10ug
Lieferbar: In stock
Listenpreis: 76,85 €
Preis: 76,85 €
lieferbar

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