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Hemofiltrate CC Chemokine-1 (72aa) (HCC-1)/CCL14, Human Europäischer Partner

ArtNr Z03214-25
Hersteller GenScript
Menge 25 ug
Quantity options 1 mg 25 ug 5 ug
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias protein/Z03214_25-Hemofiltrate_CC_Chemokine_1_72_a_a_HCC_1_CCL14_Human,
Similar products Hemofiltrate
Lieferbar
Country of Origin
USA
Shipping Temperature
4°C
Storage Conditions
-65
Product Line
PL307_Cytokines, Chemokines & Growth Factors
Description
HCC-1/CCL14 is a member of the chemokine family, which are small chemotactic proteins that regulate cell migration under inflammatory and steady state conditions. HCC-1 is expressed in epithelial and decidual cells and is unique among chemokines due to its high abundance in normal human plasma. HCC-1 can bind to chemokine receptors CCR1 and CCR5, however full length HCC-1 is a weak agonist of CCR1 and only becomes potent after removal of its eight N-terminal residues. Chemokine decoy receptor D6 can bind HCC-1 and promote its degradation as a means to regulate its level in vivo. Functionally HCC-1 promotes trophoblast migration by regulating extracellular matrix components as well as specific adhesion molecules.
Recombinant human Hemofiltrate CC Chemokine-1 (72 a.a.) (HCC-1)/CCL14 (rhHCC-1) produced in E. coli is a single non-glycosylated polypeptide chain containing 72 amino acids. A fully biologically active molecule, rhHCC-1 has a molecular mass of 8.4kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 ug
Lieferbar: In stock
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Lieferung vsl. bis 17.07.2025 

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