Hemofiltrate CC Chemokine-1 (72 a.a.) (HCC-1)/CCL14, Human

Hersteller GenScript
Typ Proteins
Specific against Human
Menge 25.0ug
ArtNr Z03214-25
eClass 6.1 34160400
eClass 9.0 42020190
HCC-1/CCL14 is a member of the chemokine family, which are small chemotactic proteins that regulate cell migration under inflammatory and steady state conditions. HCC-1 is expressed in epithelial and decidual cells and is unique among chemokines due to its high abundance in normal human plasma. HCC-1 can bind to chemokine receptors CCR1 and CCR5, however full length HCC-1 is a weak agonist of CCR1 and only becomes potent after removal of its eight N-terminal residues. Chemokine decoy receptor D6 can bind HCC-1 and promote its degradation as a means to regulate its level in vivo. Functionally HCC-1 promotes trophoblast migration by regulating extracellular matrix components as well as specific adhesion molecules.
Recombinant human Hemofiltrate CC Chemokine-1 (72 a.a.) (HCC-1)/CCL14 (rhHCC-1) produced in E. coli is a single non-glycosylated polypeptide chain containing 72 amino acids. A fully biologically active molecule, rhHCC-1 has a molecular mass of 8.4kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Product Line
PL307_Cytokines, Chemokines & Growth Factors
Storage Temperature
Shipping Temperature
Menge: 25.0ug
Lieferbar: In stock
Listenpreis: 186,82 €
Preis: 186,82 €


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