Hepatocyte Growth Factor (HGF), Human

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Hersteller GenScript
Kategorie
Typ Proteins
Specific against Human
Menge 50ug
ArtNr Z03229-50
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Hepatocyte Growth Factor (HGF), also known as hepatopoietin-A and scatter factor, is a pleiotropic mitogen belonging to the peptidase S1 family (plasminogen subfamily). It is produced by mesenchymal cells and acts on epithelial cells, endothelial cells and haemopoietic progenitor cells. HGF binds to the proto-oncogenic c-Met receptor to activate a tyrosine kinase signaling cascade. It regulates cell growth, motility and morphogenesis, thus it plays a pivotal role in angiogenesis, tumorogenesis and tissue regeneration.
Recombinant human Hepatocyte Growth Factor (rhHGF) is produced in CHO cells and consists of two polypeptide chains (alpha-chain and beta-chain) held by a single disulfide bond resulting in the formation of a biologically active heterodimer. The alpha-chain consists of 463 amino acid residues and four kringle domains. The beta-chain consists of 234 amino acid residues. A fully biologically active molecule, rhHGF has a molecular mass of around 88-90 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
Product Line
PL307_Cytokines, Chemokines & Growth Factors
Storage Temperature
-65
Shipping Temperature
4

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Menge: 50ug
Lieferbar: In stock
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