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Interleukin-10 (IL-10), Mouse Europäischer Partner

Hersteller GenScript
Kategorie
Typ Proteins
Specific against Mouse
Menge 1mg(2x500ug)
ArtNr Z02036-1
Targets IL10, CD24, IL4
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Specificity
The ED50 as determined by the dose-dependant co-stimulation with murine IL-4 of MC-9 cells was found to be <2 ng/ml, corresponding to a specific activity of 5x105 IU/mg.
Description
Interleukin-10 (IL-10), is produced by murine T-cells following their stimulation by lectins. The main source for B-cell-derived Interleukin-10 (IL-10) in mice is Ly-1 B-cells that express CD5 and CD11. Murine keratinocytes also produce Interleukin-10 (IL-10). In human Interleukin-10 (IL-10) is produced by activated CD8(+) peripheral blood T-cells, by T-helper CD4(+) T-cell clones (resembling Th0, Th1, and Th2) after both antigen-specific and polyclonal activation, by B-cell lymphomas, and by mococytes following cell activation by bacterial lipopolysaccharides and mast cells. B-cells lines derived from patients with acquired immunodeficiency syndrome and Burkitt's lymphoma constitutively secerete large quantities of Interleukin-10 (IL-10) into the conditioned medium. The synthesis of Interleukin-10 (IL-10) by monocytes is inhibited by IL-4 and IL-10. Recombinant mouse Interleukin-10 (IL-10), produced in, E. coli, is a single, non-glycosylated polypeptide chain containing 161 amino acids and having a molecular mass of 18, 885 Da.
Endotoxin Level
Less than 0.1 ng/ug (1 EU/ug) of recombinant mouse Interleukin-10 (IL-10) as determined by LAL test.
Formulation
The protein was lyophilized after extensive dialysis against 20mM PB, pH7.3, 300mM NaCl buffer.
M.W.
18, 885 Da.
Product Line
Cytokine, Chemokines & Growth Factors
Reconstitution
It is recommended to reconstitute the lyophilized recombinant mouse Interleukin-10 (IL-10) in sterile 18 Momega-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Storage
Lyophilized, Mouse Interleukin-10 (IL-10), remains stable at room temperature for three weeks, but it is best stored desiccated below -18C. Upon reconstitution Mouse Interleukin-10 (IL-10) should be stored at 4C for up to seven days. For long term storage it is recommended that a carrier protein (0.1% HSA or BSA ) be added. Avoid repeated freeze-thaw cycles.
Product Origin
USA

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1mg(2x500ug)
Lieferbar: In stock
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Lieferung vsl. bis 18.04.2024 

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