Hersteller |
GenScript
|
Kategorie |
|
Typ |
Proteins |
Specific against |
Mouse |
Format |
Sterile Filtered White lyophilized (freeze-dried) powder. |
Menge |
1 mg |
ArtNr |
Z02772-1 |
Targets |
CD121a, STAB2, NFKB1, IL33, IL13, IL5, IL4 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Specificity |
Fully biologically active when compared to standard. The ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤, 0.5 ng/ml, corresponding to a specific activity of ≥, 2.0 x 106units/mg. |
Description |
IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. |
Endotoxin Level |
Less than 0.2EU/ug of rMuIL-33 as determined by LAL method. |
Formulation |
Lyophilized from a 0.2µ, m filtered solution in PBS, EDTA and DTT, pH 7.4. |
M.W. |
Approximately 17.5 kDa protein containing 158 amino acid residues. |
Product Line |
Cytokine, Chemokines & Growth Factors |
Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20°, C. Further dilutions should be made in appropriate buffered solutions. |
Storage |
This lyophilized preparation is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles. |
Usage |
This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. |
Manufacturers Category |
Proteins |
Manufacturers Product Line |
Cytokines |
Product Origin |
USA |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.