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Fibroblast Growth Factor-7 (FGF-7), Mouse

Fibroblast Growth Factor-7 (FGF-7), Mouse

ArtNr	Z02777-10
Hersteller	GenScript
Menge	10 ug
Quantity options	1 mg 10 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers By Cell Type Carcinoma Hematology Myeloma Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Cytoskeleton Proliferation Intermediate filaments By Organ Lung Cancer
Typ	Proteins
Format	Sterile Filtered White lyophilized (freeze-dried) powder.
Specific against	Mouse (Murine, Mus musculus)
Purity	>96% by SDS-PAGE and HPLC analyses.
Sequence	MCNDMSPEQT ATSVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRIDKRGKVKGTQE MKNSYNIMEI RTVAVGIVAI KGVESEYYLA MNKEGKLYAKKECNEDCNFK ELILENHYNT YASAKWTHSG GEMFVALNQK GIPVKGKKTKKEQKTAHFLP MAIT
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	protein/Z02777-Keratinocye_Growth_Factor-1_KGF-1_Mouse, Fibroblast Growth Factor-7 (FGF-7/KGF) is one of 23 known members of the FGF family. All FGFs have two conserved cysteine residues and share 30 - 50% sequence identity at the amino acid level. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF-1/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF-1/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing.</td></tr><tr><th>M.W.</th><td colspan="7"> Approximately 18.9 kDa, a single, non-glycosylated polypeptide chain containing 164 amino acids.</td></tr><tr><th>Purity</th><td colspan="7"> >96% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> Less than 0.2EU/ug of rMuFGF-7/KGF-1 as determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using monkey 4MBr-5 cells is less than 50 ng/ml, corresponding to a specific activity of &
Similar products	Fibroblast
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Specificity	Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using monkey 4MBr-5 cells is less than 50 ng/ml, corresponding to a specific activity of ＞, 2.0 x 104 IU/mg.
Country of Origin	USA
Storage Conditions	This lyophilized preparation is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles.
Molecular Weight	Approximately 18.9 kDa, a single, non-glycosylated polypeptide chain containing 164 amino acids.
Product Line	Cytokine, Chemokines & Growth Factors
Manufacturer - Specificity	Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using monkey 4MBr-5 cells is less than 50 ng/ml, corresponding to a specific activity of ＞, 2.0 x 104 IU/mg.
Description	Fibroblast Growth Factor-7 (FGF-7/KGF) is one of 23 known members of the FGF family. All FGFs have two conserved cysteine residues and share 30 - 50% sequence identity at the amino acid level. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF-1/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF-1/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °, C. Further dilutions should be made in appropriate buffered solutions.
Formulation	Lyophilized from a 0.2µ, m filtered solution in 20mM PB, pH 8.0, 1M NaCl.
Endotoxin Level	Less than 0.2EU/ug of rMuFGF-7/KGF-1 as determined by LAL method.
Usage	This material is offered by Shanghai PrimeGene for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

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