VEGF-A164, Mouse

USA

-80°C

Vascular Endothelial Growth Factor (VEGF) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, Vascular Endothelial Growth Factor (VEGF) plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates Vascular Endothelial Growth Factor (VEGF) in the induction of tumor metastasis and intra-ocular neovascular syndromes. Vascular Endothelial Growth Factor (VEGF) signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.
Recombinant Mouse Vascular Endothelial Growth Factor A164 (VEGF-A164) produced in E.coli is a single, non-glycosylated polypeptide chain containing 165 amino acids.A fully biologically active molecule, recombinant Mouse VEGF-A164 has a molecular mass of 19.4 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.