GM-CSF, Mouse

Granulocyte Macrophage Colony Stimulating Factor (GM-CSF), was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effectors functions of granulocytes, monocytes/macrophages and eosinophils.

Lyophilized after extensive dialysis against PBS.

For research use only

Reconstituted in ddH2O or PBS at 100 ug/ml.

Proteins

USA