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IL-1β, Mouse(CHO-expressed) Europäischer Partner

Hersteller GenScript
Kategorie
Typ Proteins
Specific against Mouse
Menge 1 mg
ArtNr Z02988-1
Targets STAB2, CHRM3, CASP1, IL1B, IL1A
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Specificity
ED50, 1x108 units/mg.
Description
Interleukin-1 (IL-1), is a family of cytokines that play a central role in the regulation of immune and inflammatory responses to infections or sterile insults. IL-1alpha and IL-1beta are the first two members discovered in this family, which are the products of distinct genes recognizing the same cell surface receptors. IL-1alpha and IL-1beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa. The specific protease responsible for the processing of IL-1beta is interleukin 1beta-converting enzyme (ICE)/caspase-1. Mature human and mouse IL-1beta share approximately 75% amino acid sequence identity where human IL-1beta has been found to be active on murine cell lines. GenScript Interleukin (IL)-1beta, murine, produced in, CHO, cells, is a non-glycosylated polypeptide chain containing 152 amino acids and having a molecular mass of 17, 400 Da.
Endotoxin Level
<0.2 EU/ug, determined by LAL method.
Formulation
Lyophilized after extensive dialysis against PBS.
M.W.
17.4 kDa, observed by non-reducing SDS-PAGE.
Note
For research use only
Product Line
Cytokines, Chemokines & Growth Factors
Reconstitution
Reconstituted in ddH2O or PBS at 100 ug/ml.
Storage
Lyophilized recombinant, Murine Interleukin 1 beta (IL-1 beta), remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rmIL-1beta should be stable up to 1 week at 4C or up to 2 months at -20C.
Manufacturers Category
Proteins
Manufacturers Product Line
Cytokines
Product Origin
USA

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 04.04.2024 

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