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Beta-Defensin 1 (BD-1), Rat

Beta-Defensin 1 (BD-1), Rat

ArtNr	Z02946-1
Hersteller	GenScript
Menge	1 mg
Quantity options	1 mg 20 ug 5 ug
Kategorie	Oncology Neuroscience Neuroinflammation By Cell Type Hematology Leukemia Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Migration & Invasion By Organ Lung Cancer Heart & Blood Cancer
Typ	Proteins
Format	Sterile Filtered White lyophilized (freeze-dried) powder.
Specific against	Rat (Rattus norvegicus)
Purity	>95% by SDS-PAGE and HPLC analyses.
Sequence	DQYRCLQNGG FCLRSSCPSH TKLQGTCKPD KPNCCRS
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	protein/Z02946_1-Beta_Defensin_1_BD_1_Rat, Defensin are 3-4 kDa antimicrobial peptides of which three distinct families have been identified, alpha-defensin, beta-defensins, and insect defensins. Rat beta-Defensin 1, as a member of the beta-defensin family, is a salt-sensitive antimicrobial peptide present in epithelia of the lung and urogenital tract. The predicted amino acid sequence shows the hallmark features of other known epithelial beta-defensins, including the ordered array of six cysteine residues. </td></tr><tr><th>M.W.</th><td colspan="7"> Approximately 4.1 kDa, a single non-glycosylated polypeptide chain containing 37amino acids.</td></tr><tr><th>Purity</th><td colspan="7"> >95% by SDS-PAGE and HPLC analyses.</td></tr><tr><th>Endotoxin Level</th><td colspan="7"> Less than 1EU/ug of rRtBD1 as determined by LAL method.</td></tr><tr><th>Specific Activity</th><td colspan="7"> Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using CD34+ dendritic cells, is in a concentration range of 100.0-1000.0 ng/ml.</td></tr><tr><th>Storage</th><td colspan="7"> This lyophilized preparation is stable at 2-8C, but should be kept at -20C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -70C. Avoid repeated freeze/thaw cycles. </td></tr><tr><th>Formulation</th><td colspan="7"> Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, 500mM NaCl, pH 7.0.</td></tr><tr><th>Reconstitution</th><td colspan="7"> We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <=-20C. Further dilutions should be made in appropriate buffered solutions.</td></tr><tr><th>Physical Appearance</th><td colspan="7"> Sterile Filtered White lyophilized (freeze-dried) powder.</td></tr><tr><th>Sequence</th><td colspan="7"> DQYRCLQNGG FCLRSSCPSH TKLQGTCKPD KPNCCRS </td></tr>
Similar products	Beta-Defensin
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Specificity	Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using CD34+ dendritic cells, is in a concentration range of 100.0-1000.0 ng/ml.
Country of Origin	USA
Storage Conditions	This lyophilized preparation is stable at 2-8C, but should be kept at -20C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -70C. Avoid repeated freeze/thaw cycles.
Molecular Weight	Approximately 4.1 kDa, a single non-glycosylated polypeptide chain containing 37amino acids.
Product Line	Cytokine, Chemokines & Growth Factors
Manufacturer - Specificity	Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using CD34+ dendritic cells, is in a concentration range of 100.0-1000.0 ng/ml.
Description	Defensin are 3-4 kDa antimicrobial peptides of which three distinct families have been identified, alpha-defensin, beta-defensins, and insect defensins. Rat beta-Defensin 1, as a member of the beta-defensin family, is a salt-sensitive antimicrobial peptide present in epithelia of the lung and urogenital tract. The predicted amino acid sequence shows the hallmark features of other known epithelial beta-defensins, including the ordered array of six cysteine residues.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <=-20C. Further dilutions should be made in appropriate buffered solutions.
Formulation	Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, 500mM NaCl, pH 7.0.
Endotoxin Level	Less than 1EU/ug of rRtBD1 as determined by LAL method.

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Z02946-1-datasheet.pdf

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Menge: 1 mg

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