Interleukin-3 beta (IL-3 beta), Rat

Hersteller GenScript
Kategorie
Typ Proteins
Specific against Rat
Menge 10.0ug 
ArtNr Z03165-10
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Description
Interleukin-3 (IL-3) is a pleiotropic cytokine belonging to the interleukin family. IL-3 shares similarities with Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) and IL-5: they all have a four-helix bundle structure, are located on the same chromosomes in both human and mouse, are produced by activated T cells, and share receptors. The IL-3/IL-5/GM-CSF receptor family members are all heterodimeric, composed of a receptor-specific alpha chain and a common beta chain. IL-3 is also called multi-colony stimulating factor since it stimulates the development and colony formation of multiple lineages of hematopoietic cells by activating intracellular pathways such as Ras-Raf-ERK and JAK/STAT. IL-3 inhibits apoptosis and promotes cell survival by targeting the anti-apoptotic bcl-2 gene family.
Recombinant rat Interleukin-3 beta (rrIL-3 beta) produced in E. coli is a single non-glycosylated polypeptide chain containing of 144 amino acids. A fully biologically active molecule, rrIL-3 beta has a molecular mass of 16.3 kDa analyzed by non-reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Product Line
PL307_Cytokines, Chemokines & Growth Factors
Storage Temperature
-65
Shipping Temperature
4
Menge: 10.0ug 
Lieferbar: In stock
Listenpreis: 69,86 €
Preis: 69,86 €
lieferbar

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