Rabbit anti Human Resistin (a.a. 79-90)

GWB-F7AAE4

Peptide corresponding to a. a. 79-90 of human resistin.

Recognizes human resistin (14kDa). It has been suggested that the hormone resistin secreted by adipocytes links obesity to type 2 diabetes by modulating steps in the insulin-signaling pathway and inducing insulin resistance. Levels of circulating resistin decrease following treatment with the anti diabetic drug rosiglitazone and increase in diet-induced and genetic forms of obesity. In addition treatment of normal mice with recombinant resistin impairs glucose tolerance and insulin action. Insulin-stimulated glucost uptake by adipocytes is enhanced by neutralization of resistin and is reduced by resistin treatment.

1mg/ml (OD280)Preservatives: NaN3

This product contains sodium azide which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0. 1â ??1. 0%. When disposing of this reagent through lead or copper plumbing flush with copious volumes of water to prevent azide build-up in drains. Rabbit anti Human Resistin (a. a. 79-90). Rabbit Antibody to Human Resistin (amino acids 79-90)

Homodimer; disulfide-linked (By similarity).

Expressed only in fatty tissues.