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Goat anti Human Serum IgA alpha

ArtNr 18-511-244964
Hersteller GENWAY
Menge 0.1mg
Kategorie
Typ Antibody
Specific against Human (Homo sapiens)
Host Goat
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-C06F90
Similar products 18-511-244964
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Genway ID:
GWB-C06F90
Host Animal:
Goat
Specificity:
IgA Serum
Specificity:
Based on immunoelectrophoresis the antibody reacts with the heavy chain portion of human IgA. The antibody does not react with the heavy chains on human IgG or IgM or with light chains common to most human immunoglobulins. No antibody was detected against non-immunoglobulin serum proteins but antibodies may cross-react with IgA from other species.
Type of Product:
Polyclonal Antibodies to Human Immunoglobulins
Concentration:
0. 8mg/ml (prior to lyophilization)
Buffer:
Lyophilized from 0. 01M Sodium phosphate 0. 25M Sodium chloride pH 7. 6 containing 15mg/ml BSAApplications Notes : A dilution range of 1:500?1:5 000 is suggested for immunohistochemistry on tissue sections 1:5 000?1:100 000 for ELISA and Western blotting with chromogenic substrates and 1:10 000?1:200 000 for Western blotting with ECL substrates. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. Goat anti Human Serum IgA alpha. Goat Antibody to Human Serum Immunoglobulin A (IgA) Alpha chain. Horseradish Peroxidase conjugated
Function:
Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:
Monomeric or polymeric.
Ptm:
3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:
A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:
Contains 3 Ig-like (immunoglobulin-like) domains.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1mg
Lieferbar: In stock
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