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Goat anti Human Serum IgA alpha

Goat anti Human Serum IgA alpha

Item no.	18-511-244964
Manufacturer	GENWAY
Amount	0.1mg
Category	Oncology Antibodies By Cell Type Hematology Lymphoma Secondary Antibodies By Organ Lymphatic System Cancer
Type	Antibody
Specific against	Human (Homo sapiens)
Host	Goat
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-C06F90
Similar products	18-511-244964
Available
Genway ID:	GWB-C06F90
Host Animal:	Goat
Specificity:	IgA Serum
Specificity:	Based on immunoelectrophoresis the antibody reacts with the heavy chain portion of human IgA. The antibody does not react with the heavy chains on human IgG or IgM or with light chains common to most human immunoglobulins. No antibody was detected against non-immunoglobulin serum proteins but antibodies may cross-react with IgA from other species.
Type of Product:	Polyclonal Antibodies to Human Immunoglobulins
Concentration:	0. 8mg/ml (prior to lyophilization)
Buffer:	Lyophilized from 0. 01M Sodium phosphate 0. 25M Sodium chloride pH 7. 6 containing 15mg/ml BSAApplications Notes : A dilution range of 1:500?1:5 000 is suggested for immunohistochemistry on tissue sections 1:5 000?1:100 000 for ELISA and Western blotting with chromogenic substrates and 1:10 000?1:200 000 for Western blotting with ECL substrates. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. Goat anti Human Serum IgA alpha. Goat Antibody to Human Serum Immunoglobulin A (IgA) Alpha chain. Horseradish Peroxidase conjugated
Function:	Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:	Monomeric or polymeric.
Ptm:	3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:	A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:	Contains 3 Ig-like (immunoglobulin-like) domains.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1mg

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Delivery expected until 11/27/2025

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