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RABBIT ANTI HUMAN BRS-3

ArtNr 18-783-313737
Hersteller GENWAY
Menge 0.05 mg
Kategorie
Typ Antibody
Specific against Human (Homo sapiens)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-D10DF5
Similar products 18-783-313737
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Genway ID:
GWB-D10DF5
Specificity:
BRS-3
Isotype:
Polyclonal IgGSpecies Cross Reactivity: Based on sequence similarity is expected to react with:Rat MouseN. B. Antibody reactivity and working conditions may vary between species.
Buffer Solution:
Phosphate buffered saline pH7. 7
Preservative Stabilisers:
0. 01% Sodium Azide (NaN3)Approx. Protein Concentrations: IgG concentration 1. 0mg/ml
Immunogen:
Synthetic peptide: 1st cytoplasmic domain of human BRS-3 conjugated to Keyhole Limpet Hemocyanin (KLH).
Specificity:
Detects bombesin-like receptor-3 (BRS-3) a heptahelical G protein-coupled receptor. BRS-3 is thought to function as a receptor for bombesin-like peptides; which modulate smooth-muscle contraction exocrine and endocrine processes metabolism and behaviour. BRS-3 is thought to be particularly important in regulating obesity and metabolic control of insulin and glucose. BRS-3 expression in secondary spermatocytes suggests BRS-3 has a role in sperm cell division maturation or function. BRS-3 could also serve as a potential therapeutic target in human lung carcinoma. Recommended Secondary Antibodies: Sheep Anti Rabbit IgGGoat Anti Rabbit IgG (Fc)Goat Anti Rabbit IgG (H/L)
Function:
Role in sperm cell division maturation or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Subcellular locationCell membrane; Multi-pass membrane protein. Tissue specificityIn germ cells in testis. Lung carcinoma cells. Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.05 mg
Lieferbar: In stock
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