Comparison

RABBIT ANTI HUMAN BRS-3

Item no. 18-783-313737
Manufacturer GENWAY
Amount 0.05 mg
Category
Type Antibody
Specific against Human (Homo sapiens)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-D10DF5
Similar products 18-783-313737
Available
Genway ID:
GWB-D10DF5
Specificity:
BRS-3
Isotype:
Polyclonal IgGSpecies Cross Reactivity: Based on sequence similarity is expected to react with:Rat MouseN. B. Antibody reactivity and working conditions may vary between species.
Buffer Solution:
Phosphate buffered saline pH7. 7
Preservative Stabilisers:
0. 01% Sodium Azide (NaN3)Approx. Protein Concentrations: IgG concentration 1. 0mg/ml
Immunogen:
Synthetic peptide: 1st cytoplasmic domain of human BRS-3 conjugated to Keyhole Limpet Hemocyanin (KLH).
Specificity:
Detects bombesin-like receptor-3 (BRS-3) a heptahelical G protein-coupled receptor. BRS-3 is thought to function as a receptor for bombesin-like peptides; which modulate smooth-muscle contraction exocrine and endocrine processes metabolism and behaviour. BRS-3 is thought to be particularly important in regulating obesity and metabolic control of insulin and glucose. BRS-3 expression in secondary spermatocytes suggests BRS-3 has a role in sperm cell division maturation or function. BRS-3 could also serve as a potential therapeutic target in human lung carcinoma. Recommended Secondary Antibodies: Sheep Anti Rabbit IgGGoat Anti Rabbit IgG (Fc)Goat Anti Rabbit IgG (H/L)
Function:
Role in sperm cell division maturation or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Subcellular locationCell membrane; Multi-pass membrane protein. Tissue specificityIn germ cells in testis. Lung carcinoma cells. Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.05 mg
Available: In stock
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