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Mouse Anti-Human IgA1 (1 chain specific)

Mouse Anti-Human IgA1 (1 chain specific)

ArtNr	20-787-275972
Hersteller	GENWAY
Menge	1 ml
Kategorie	Oncology Antibodies Immunohistochemistry Western Blot ELISA Immunocytochemistry Secondary Antibodies By Organ Lymphatic System Cancer Dot Blot
Typ	Antibody
Applikationen	WB, IHC, ICC, ELISA, DB
Clon	B3506B4
Specific against	Human (Homo sapiens)
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-59CB50
Similar products	20-787-275972
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Genway ID:	GWB-59CB50
Isotype:	Mouse IgG1 kappa
Clone:	B3506B4
Characterization:	To insure lot-to-lot consistency each batch of product is tested by ELISA for conformance to characteristics of a standard reference reagent.
Specificity:	Reacts with the Fc portion of the heavy chain of human IgA1 as demonstrated by ELISA
Working Dilution:	ELISA: 1:500-1:1 000
Warning:	Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin eyes or clothing. Wear eye or face protection when handling. If skin or eye contact occurs wash with copious amounts of water. If ingested or inhaled contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Function:	Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:	Monomeric or polymeric.
Ptm:	3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:	A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:	Contains 3 Ig-like (immunoglobulin-like) domains.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 1 ml

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Lieferung vsl. bis 11.09.2025

Express-Lieferung: 3 Tage sparen

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