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Mouse Anti-Human IgA1 (1 chain specific)

Mouse Anti-Human IgA1 (1 chain specific)

Item no.	20-787-275972
Manufacturer	GENWAY
Amount	1 ml
Category	Oncology Antibodies Immunohistochemistry Western Blot ELISA Immunocytochemistry Secondary Antibodies By Organ Lymphatic System Cancer Dot Blot
Type	Antibody
Applications	WB, IHC, ICC, ELISA, DB
Clone	B3506B4
Specific against	Human (Homo sapiens)
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-59CB50
Similar products	20-787-275972
Available
Genway ID:	GWB-59CB50
Isotype:	Mouse IgG1 kappa
Clone:	B3506B4
Characterization:	To insure lot-to-lot consistency each batch of product is tested by ELISA for conformance to characteristics of a standard reference reagent.
Specificity:	Reacts with the Fc portion of the heavy chain of human IgA1 as demonstrated by ELISA
Working Dilution:	ELISA: 1:500-1:1 000
Warning:	Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin eyes or clothing. Wear eye or face protection when handling. If skin or eye contact occurs wash with copious amounts of water. If ingested or inhaled contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Function:	Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:	Monomeric or polymeric.
Ptm:	3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:	A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:	Contains 3 Ig-like (immunoglobulin-like) domains.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 ml

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Delivery expected until 9/11/2025

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