Vergleich

Rabbit anti Mouse Vitronectin

ArtNr 18-511-245449
Hersteller GENWAY
Menge 1ml
Kategorie
Typ Antibody
Applikationen WB, IHC, ELISA
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-794F8F
Similar products 18-511-245449
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Genway ID:
GWB-794F8F
Host Animal:
Rabbit
Immunogen:
Mouse Vitronectin
Specificity:
Vitronectin
Specificity:
Mouse Vitronectin
Type of Product:
Polyclonal Antibodies to Platelets and Hemostasis Antigens
Concentration:
Lot specific (OD280nm E0. 1% = 1. 36)
Buffer:
0. 05M Sodium Phosphate pH 6. 6 containing 0. 1M Sodium chloride 1mM EDTAApplications Notes : Suitable for use in ELISA Western blot and Immunohistochemistry (frozen sections). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. Rabbit anti Mouse Vitronectin. Rabbit Antibody to Mouse Vitronectin
Function:
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.
Function:
Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.
Subunit:
Exists in two forms: a single chain 75 kDa form (V75) and a clipped form composed of two chains (65 kDa and 10 kDa) (V65+V10) which are held together by a disulfide bond. Interacts with SERPINE1/PAI1 and insulin.
Subcellular Location:
Secreted extracellular space.
Tissue Specificity:
Plasma.
Domain:
The SMB domain mediates interaction with SERPINE1/PAI1. The heparin-binding domain mediates interaction with insulin.
Ptm:
Sulfated on 2 tyrosine residues.
Ptm:
N- and O-glycosylated (By similarity).
Ptm:
Phosphorylation on Thr-69 and Thr-76 favors cell adhesion and spreading.
Ptm:
It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.
Similarity:
Contains 4 hemopexin-like domains.
Similarity:
Contains 1 SMB (somatomedin-B) domain.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1ml
Lieferbar: In stock
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