TAF7L

ArtNr	18-003-44003
Hersteller	GENWAY
Menge	0.1 mg
Kategorie	Oncology Antibodies Western Blot Primary Antibodies By Organ Testicular & Prostate Cancer
Typ	Antibody
Applikationen	WB
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-4504ED
Similar products	18-003-44003
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Genway ID:	GWB-4504ED
Antigen Specificity:	Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human Taf7l.
ELISA Titre:	1:1562500
Category:	TF for Mouse
Note:	Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. TAF7I belongs to the family of TATA box binding protein (Tbp)-associated factors. Promoter selectivity for all three classes of eukaryotic RNA polymerases is brought about by multimeric protein complexes containing TATA box binding protein (TBP) and speci
Function:	Probably functions as a spermatogensis-specific component of the DNA-binding general transcription factor complex TFIID a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis.
Subunit:	TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). TAF7L may replace TAF7 in a spermatogenensis-specific form of TFIID. Interacts with TBP; the interaction occurs in a sub-population of cells (pachytene and haploid round spermatids) and is developmentally regulated through differential intracellular localization of the two proteins. Interacts with TAF1.
Subcellular Location:	Nucleus. Cytoplasm. Note=Cytoplasmic in spermatogonia and early spermatocytes (preleptotene leptotene and zygotene); translocates into the nuclei of pachytene spermatocytes and round spermatids.
Tissue Specificity:	Testis-specific (at protein level). Expressed during spermatogenesis from spermatogonia stage up to the stage of round spermatids.
Miscellaneous:	Null mice resulted in reduced sperm count and motility.
Similarity:	Belongs to the TAF7 family. Pointud. J. C. . et al. . (2003) J. Cell. Sci. 116 (PT 9). 1847-1858.

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Menge: 0.1 mg

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