TAF7L

Item no.	18-003-44003
Manufacturer	GENWAY
Amount	0.1 mg
Category	Oncology Antibodies Western Blot Primary Antibodies By Organ Testicular & Prostate Cancer
Type	Antibody
Applications	WB
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-4504ED
Similar products	18-003-44003
Available
Genway ID:	GWB-4504ED
Antigen Specificity:	Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human Taf7l.
ELISA Titre:	1:1562500
Category:	TF for Mouse
Note:	Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. TAF7I belongs to the family of TATA box binding protein (Tbp)-associated factors. Promoter selectivity for all three classes of eukaryotic RNA polymerases is brought about by multimeric protein complexes containing TATA box binding protein (TBP) and speci
Function:	Probably functions as a spermatogensis-specific component of the DNA-binding general transcription factor complex TFIID a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis.
Subunit:	TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). TAF7L may replace TAF7 in a spermatogenensis-specific form of TFIID. Interacts with TBP; the interaction occurs in a sub-population of cells (pachytene and haploid round spermatids) and is developmentally regulated through differential intracellular localization of the two proteins. Interacts with TAF1.
Subcellular Location:	Nucleus. Cytoplasm. Note=Cytoplasmic in spermatogonia and early spermatocytes (preleptotene leptotene and zygotene); translocates into the nuclei of pachytene spermatocytes and round spermatids.
Tissue Specificity:	Testis-specific (at protein level). Expressed during spermatogenesis from spermatogonia stage up to the stage of round spermatids.
Miscellaneous:	Null mice resulted in reduced sperm count and motility.
Similarity:	Belongs to the TAF7 family. Pointud. J. C. . et al. . (2003) J. Cell. Sci. 116 (PT 9). 1847-1858.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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