Alpha-1A adrenergic receptor

3rd cytoplasmic domain of human. Synthetic peptide - KLH conjugated.
Summary of Expression: The alpha 1c- Adrenergic Receptor also known as alpha 1aadrenoceptor is activated by epinephrine and norepinephrine. This receptor mediates calcium release upon ligand binding. The alpha 1-c adrenoceptor is one of three subtypes of alpha 1-adrenergic receptor (alpha 1 c/a alpha 1b and alpha 1d). The alpha 1c receptor couples to phospholipase C via a GTP-binding protein insensitive to pertussis toxin. Three isoforms are generated by alternative splicing. However the corresponding isoforms of the protein have similar ligand-binding properties effector coupling and tissue distribution.