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Sheep anti Dog Urokinase

Sheep anti Dog Urokinase

Catalytic
ArtNr	18-511-244844
Hersteller	GENWAY
Menge	1 mg
Kategorie	Oncology Antibodies Western Blot ELISA Cardiovascular Research Atherosclerosis Primary Antibodies By Organ Testicular & Prostate Cancer
Typ	Antibody
Applikationen	WB, ELISA
Specific against	other
Host	Sheep
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-79EC1E
Similar products	18-511-244844
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Genway ID:	GWB-79EC1E
Host Animal:	Sheep
Immunogen:	Recombinant Dog uPA
Specificity:	Urokinase (uPA)
Specificity:	Recognizes Dog uPA both alone and in complex under reducing and native conditions.
Type of Product:	Polyclonal Antibodies to Enzymes
Concentration:	Lot specific (OD280nm E0. 1% = 1. 36)
Buffer:	0. 05M Sodium phosphate pH 6. 6 containing 0. 1M Sodium chloride and 1mM EDTAApplications Notes : Suitable for use in ELISA (1:100 000) and Western blot (1-5 ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. Sheep anti Dog Urokinase. Sheep Antibody to Dog Urokinase (uPA)
Function:	Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.
Activity:	Specific cleavage of Arg-\|-Val bond in plasminogen to form plasmin.
Subunit:	Found in high and low molecular mass forms. Each consists of two chains A and B. The high molecular mass form contains a long chain A which is cleaved to yield a short chain A. Binds LRP1B; binding is followed by internalization and degradation. Interacts with MRC2. Interacts with PLAUR.
Subcellular Location:	Secreted.
Tissue Specificity:	Expressed in the prostate gland and prostate cancers.
Ptm:	Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding. Pharmaceutical: Available under the name Abbokinase (Abbott). Used in Pulmonary Embolism (PE) to initiates fibrinolysis. Clinically used for therapy of thrombolytic disorders.
Similarity:	Belongs to the peptidase S1 family [view classification].
Similarity:	Contains 1 EGF-like domain.
Similarity:	Contains 1 kringle domain.
Similarity:	Contains 1 peptidase S1 domain [view classification].

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 1 mg

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Lieferung vsl. bis 11.09.2025

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