« Back
Home /
Sheep anti Dog Urokinase

Sheep anti Dog Urokinase

Catalytic
Item no.	18-511-244844
Manufacturer	GENWAY
Amount	1 mg
Category	Oncology Antibodies Western Blot ELISA Cardiovascular Research Atherosclerosis Primary Antibodies By Organ Testicular & Prostate Cancer
Type	Antibody
Applications	WB, ELISA
Specific against	other
Host	Sheep
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-79EC1E
Similar products	18-511-244844
Available
Genway ID:	GWB-79EC1E
Host Animal:	Sheep
Immunogen:	Recombinant Dog uPA
Specificity:	Urokinase (uPA)
Specificity:	Recognizes Dog uPA both alone and in complex under reducing and native conditions.
Type of Product:	Polyclonal Antibodies to Enzymes
Concentration:	Lot specific (OD280nm E0. 1% = 1. 36)
Buffer:	0. 05M Sodium phosphate pH 6. 6 containing 0. 1M Sodium chloride and 1mM EDTAApplications Notes : Suitable for use in ELISA (1:100 000) and Western blot (1-5 ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. Sheep anti Dog Urokinase. Sheep Antibody to Dog Urokinase (uPA)
Function:	Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.
Activity:	Specific cleavage of Arg-\|-Val bond in plasminogen to form plasmin.
Subunit:	Found in high and low molecular mass forms. Each consists of two chains A and B. The high molecular mass form contains a long chain A which is cleaved to yield a short chain A. Binds LRP1B; binding is followed by internalization and degradation. Interacts with MRC2. Interacts with PLAUR.
Subcellular Location:	Secreted.
Tissue Specificity:	Expressed in the prostate gland and prostate cancers.
Ptm:	Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding. Pharmaceutical: Available under the name Abbokinase (Abbott). Used in Pulmonary Embolism (PE) to initiates fibrinolysis. Clinically used for therapy of thrombolytic disorders.
Similarity:	Belongs to the peptidase S1 family [view classification].
Similarity:	Contains 1 EGF-like domain.
Similarity:	Contains 1 kringle domain.
Similarity:	Contains 1 peptidase S1 domain [view classification].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1 mg

available

Delivery expected until 9/11/2025

Express Delivery: Save 7 days

Compare

Add to wishlist

Get an offer