CD253


ArtNr	18-783-75597
Hersteller	GENWAY
Menge	0.1 mg
Kategorie	Oncology Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies By Organ Breast Cancer
Typ	Antibody
Applikationen	WB, IHC, ELISA
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-B1271C
Similar products	18-783-75597
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Genway ID:	GWB-B1271C
Specificity:	CD253NCBI
Gene ID:	8743
Specificity:	CD253
Immunogen:	Recombinant human CD253
Immunohistology:	This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6. 0 is recommended for this purpose. Histology: Metastatic carcinoma of lymph node from breast tissue
Antiserum Preparation:	Antisera to human CD253 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		None present Reconstitution: Reconstitute with 0. 1ml distilled water. For long term storage the addition of 0. 09% sodium azide is recommended. Suggested
Dilution:	Suggested
Dilution:	Immunohistology - Paraffin - 0. 25ug/mlmmunohistology - Resin - 0. 5ug/mlWestern Blotting - 0. 1 - 0. 2ug/ml
Function:	Cytokine that binds to TNFRSF10A/TRAILR1 TNFRSF10B/TRAILR2 TNFRSF10C/TRAILR3 TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3 TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. Cofactor: Binds 1 zinc ion per trimer.
Subunit:	Homotrimer.
Subcellular Location:	Membrane; Single-pass type II membrane protein (Potential).
Tissue Specificity:	Widespread; most predominant in spleen lung and prostate.
Similarity:	Belongs to the tumor necrosis factor family. 1. Almasan. A. and Ashkenazi. A. (2003) Apo2L/TRAIL: apoptosis signaling. biology and potential for cancer therapy.

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Menge: 0.1 mg

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Lieferung vsl. bis 27.11.2025

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