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ANGIOTENSIN II

ArtNr 18-783-77314
Hersteller GENWAY
Menge 1 ml
Kategorie
Typ Antibody
Applikationen ELISA
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-31E10F
Similar products 18-783-77314
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Genway ID:
GWB-31E10F
Specificity:
ANGIOTENSIN II
Specificity:
ANGIOTENSIN II
Immunogen:
RSA/RaIg conjugated
Specificity Note:
This product is specific for Angiotensin II and shows the following cross-reactivities with other forms of Angiotensin:Angiotensin III 75%Angiotensin I 20% Angiotensin II is formed by cleavage of the terminal two amino acid residues of Angiotensin I by ACE (Angiotensin-converting enzyme). It is mainly found in lung capillaries where it increases blood pressure before being degraded to Angiotensin III by cleavage of the N-terminal aspartic acid residue.
Preparation:
Ig fraction prepared by ammonium sulphate precipitation
Buffer Solution:
Phosphate buffered saline pH 7. 2
Preservative Stabilisers:
0. 09% Sodium Azide (NaN3) 1% Bovine Serum Albumin Summary: The protein encoded by this gene pre-angiotensinogen or angiotensinogen precursor is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Summary: The protein encoded by this gene pre-angiotensinogen or angiotensinogen precursor is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension and can cause renal tubular dysgenesis a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation and inflammatory bowel disease. [provided by RefSeq].

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 ml
Lieferbar: In stock
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