FIBRONECTIN


ArtNr	18-783-78954
Hersteller	GENWAY
Menge	1 ml
Kategorie	Oncology Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Cell Biology Cell Movement Cell Adhesion Western Blot ELISA Cell Stainings ECM Primary Antibodies
Typ	Antibody
Applikationen	WB, ELISA
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-8E7DE4
Similar products	18-783-78954
Lieferbar
Genway ID:	GWB-8E7DE4
Specificity:	FIBRONECTIN
Isotype:	Polyclonal IgG
Immunogen:	Purified murine fibronectin
Specificity Note:	This product recognises fibronectin a 460-500kD glycoprotein involved in tissue organisation and wound repair.
Preparation:	Ig fraction prepared by ammonium sulphate precipitation
Buffer Solution:	0. 05 M NH4HCO3
Preservative Stabilisers:		None present Reconstitution: Reconstitute in 1 ml of sterile distilled water. For long term storage the addition of a preservative is recommended. Suggested
Dilution:	Suggested
Dilution:	Western Blotting - 1/300 - 1/400
Function:	Fibronectins bind cell surfaces and various compounds including collagen fibrin heparin DNA and actin. Fibronectins are involved in cell adhesion cell motility opsonization wound healing and maintenance of cell shape.
Subunit:	Mostly heterodimers or multimers of alternatively spliced variants connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Interacts with FBLN1 FBLN7 AMBP TNR LGALS3BP and COL13A1 (By similarity).
Subcellular Location:	Secreted extracellular space extracellular matrix.
Tissue Specificity:	Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms) made by fibroblasts epithelial and other cell types is deposited as fibrils in the extracellular matrix.
Ptm:	Sulfated (By similarity).
Ptm:	Forms covalent cross-links mediated by a transglutaminase such as F13A or TGM2 between a glutamine and the epsilon-amino group of a lysine residue forming homopolymers and heteropolymers (e. g. fibrinogen-fibronectin collagen-fibronectin heteropolymers).
Similarity:	Contains at least 2 fibronectin type-I domains. 1. Koya. D. et al. (2000) Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice. a rodent model for type 2 diabetes.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkt-Datenblatt anfordern

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 1 ml

lieferbar

Lieferung vsl. bis 27.11.2025

Express-Lieferung: 7 Tage sparen

Vergleichen

Auf den Wunschzettel

Angebot anfordern