PP2C alpha

GWB-628AC0

A synthetic peptide corresponding to residues near the C-terminal of human PP2C alpha protein was used as an immunogen.

WB: 1:1 000-5 000IHC: 1:100 - 250ICC: 1: 100 - 250FC: 1:50IP: 1:50. Protein phosphatase 2C (PP2C) is a family of serine/threonine specific protein phosphatases. PP2C is a 42 kDa monomeric enzyme with broad substrate specificity and its activity is depended upon divalent cations (e. g. magnesium) (1). In mammals three members of PP2C family are known; PP2C -alpha -beta and -gamma. PP2C 1. Baudouin E. et al. Plant Journal 20(3):343-348 1999. 2. Takekawa M. et al EMBO J. 17: 4744-4752 1998. 3. Lammers T et al. Molecular Cancer. 6:65 2007. 4. Manufactured under U. S. Patents No. 5 675 063 and 7 429 487