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Alcohol Dehydrogenase [1E5]

Alcohol Dehydrogenase [1E5]

ArtNr	20-272-192883
Hersteller	GENWAY
Menge	0.1 mg
Kategorie	Oncology Antibodies Immunocytochemistry Primary Antibodies By Organ Heart & Blood Cancer
Typ	Antibody
Applikationen	ICC
Clon	1E5
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-938A52
Similar products	20-272-192883
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Genway ID:	GWB-938A52
Clone:	1E5
Isotype:	IgG1
Immunogen:	Purified alcohol dehydrogenase from human liver
Antigen Species:	Human
Specificity:	This antibody is against human Alcohol Dehydrogenase (ADH). This antibody reacts with ADH with Kd=10-10M This antibody does not influence oxidoreductase activity
Target:	Alcohol Dehydrogenase
Localization:	Cytoplasmic
Concentration:	2 mg/ml Storage
Buffer:	Phophate-buffered saline pH 7. 4 containing 0. 1% sodium azide
Application Note:	Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. Cellular
Localization:	Cytoplasmic Myeloma: Sp2/0 ADH (alcohol dehydrogenase) family of proteins metabolize a variety of substances such as ethanol retinal other aliphatic alcohol hydroxysteroids and lipid peroxidation products. With the coenzyme NAD ADH catalyzes the reversible conversion of organic alcohol to ketones or aldehydes. ADH play a major role in ethanol metabolism. Immunocytochemical analysis of hepatocyte differentiation.
Catalytic Activity:	An alcohol + NAD+ = an aldehyde or ketone + NADH. Cofactor: Binds 2 zinc ions per subunit.
Subunit:	Dimer of identical or non-identical chains of three types (A B C) which are coded by 3 separate genes at different loci.
Subcellular Location:	Cytoplasm.
Tissue Specificity:	Expressed at high levels in the liver small intestine and eye at moderate levels in kidney ovary and uterus and at low levels in the spinal cord thymus heart stomach mucosa skin and testis.
Similarity:	Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily.

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