17-BETA-ESTRADIOL


ArtNr	20-783-73554
Hersteller	GENWAY
Menge	0.2 mg
Kategorie	Oncology Antibodies ELISA Primary Antibodies By Organ Testicular & Prostate Cancer
Typ	Antibody
Applikationen	ELISA
Clon	4S11 (BGN/06
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-F8E548
Similar products	20-783-73554
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Genway ID:	GWB-F8E548
Isotype:	IgG1
Specificity:	17-BETA-ESTRADIOL. 20-783-73554 is specific for 17-beta estradiol a mammalian estrogenic hormone produced in the ovaries placenta and testis that has a role in normal sexual development and the regulation of the menstrual cycle. 20-783-73554 exhibits negligible cross reactivity with estriol and testosterone.
Specificity:	17-BETA-ESTRADIOL
Clone:	4S11 (BGN/06/8811)
Immunogen:	17-beta estradiol conjugated to bovine serum albumin at position 6.
Preparation:	Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution:	Phosphate buffered saline pH 7. 2
Preservative Stabilisers:		0. 09% Sodium Azide (NaN3)
Function:	The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1) lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
Catalytic Activity:	2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-(2-methylpropanoyl)dihydrolipoyl)lysine. Cofactor: Binds 1 lipoyl cofactor covalently.
Subunit:	Forms a 24-polypeptide structural core with octahedral symmetry.
Subcellular Location:	Mitochondrion matrix.
Disease:	Defects in DBT are the cause of maple syrup urine disease type 2 (MSUD2) [MIM:248600]. MSUD is an autosomal recessive disorder characterized by mental and physical retardation feeding problems and a maple syrup odor to the urine.
Miscellaneous:	The catalytic function of this enzyme is to accept and to transfer to coenzyme A acyl groups that are generated by the branched-chain alpha-keto acid decarboxylase component.
Similarity:	Belongs to the 2-oxoacid dehydrogenase family.
Similarity:	Contains 1 lipoyl-binding domain.

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Menge: 0.2 mg

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