Vergleich

Ubiquitin (a.a. 64-76)

ArtNr 20-511-240125
Hersteller GENWAY
Menge 0,2 ml
Kategorie
Typ Antibody
Applikationen WB, IP, IHC, ELISA
Clon 39593
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-1E14EE
Similar products 20-511-240125
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Genway ID:
GWB-1E14EE
Isotype:
IgG1. k
Clone:
39593Host Animal: Mouse
Specificity:
Ubiquitin (a. a. 64-76)
Type of Product:
Monoclonal Antibodies for Neuroscience
Concentration:
~2mg/ml (Bradford & ELISA assays)
Buffer:
Not applicable. Applications Notes : ELISA (1:10 000 1:100 000). Western blot (1:1 000 ? 1:100 000). Immunoprecipitation (1:10 ? 1:100). Immunohistochemistry on unfixed tissues (1:100 ? 1:10 000). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. MAb to Ubiquitin (a. a. 64-76). Monoclonal Antibody to Ubiquitin (amino acids 64-76)
Function:
Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions including maintenance of chromatin structure regulation of gene expression stress response ribosome biogenesis and DNA repair.
Subcellular Location:
Cytoplasm. Nucleus.
Ptm:
Several types of polymeric chains can be formed depending on the lysine used for the assembly.
Miscellaneous:
Ubiquitin is synthesized as a polyubiquitin precursor with exact head to tail repeats the number of repeats differ between species and strains. In some species there is a final amino-acid after the last repeat here in human a Val. Some ubiquitin genes contain a single copy of ubiquitin fused to a ribosomal protein (either L40 or S27a).
Similarity:
Belongs to the ubiquitin family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0,2 ml
Lieferbar: In stock
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