CD62L

CD62LNCBI

CD62L

PHA stimulated lymphoblasts.

Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.

Flow Cytometry - 1/50 - 1/100

Interaction with PSGL1/SELPLG is required for promoting recruitment and rolling of leukocytes. This interaction is dependent on the sialyl Lewis X glycan and tyrosine sulfation modifications of PSGL1. Sulfation on Y-51 of PSGL1 is important for L-selectin binding.

Expressed in B cell lines and T lymphocytes.

Contains 1 C-type lectin domain.

Contains 2 Sushi (CCP/SCR) domains. 1. Pilarski. L. M. et al. (1991) FMC46. a cell protrusion-associated leucocyte adhesion molecule-1 epitope on human lymphocytes and thymocytes. 2. Zola. H. et al. (1991) The expression of sub-population markers on B cells: A re-evaluation using high sensitivity fluorescence flow cytometry. 3. Sopp. P. and Howard. C. C. (1997) Cross-reactivity of monoclonal antibodies to defined human leucocyte diferentiation antigens with bovine cells. 4. Yoshino. N. et al. (2000) Upgrading of flow cytometric analysis for absolute counts. cytokines and other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies.