Hersteller |
GENWAY
|
Kategorie |
|
Typ |
Antibody |
Specific against |
other |
Clon |
Y9A2 |
Applikationen |
FC, IP |
Menge |
0.025 mg |
ArtNr |
20-783-310118 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Genway ID: |
GWB-F161F0 |
Specificity: |
INTEGRIN ALPHA 9 BETA 1NCBI |
Gene ID: |
3680 |
Specificity: |
INTEGRIN ALPHA 9 BETA 1 |
Clone: |
Y9A2 |
Immunogen: |
alpha9 integrin transfected lambda cells. |
Fusion Partner: |
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line. |
Preparation: |
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant |
Buffer Solution: |
Phosphate buffered saline pH7. 4 |
|
Preservative Stabilisers: |
| 0. 09%Sodium AzideSuggested |
Flow Cytometry: |
Use 10ul of the suggested working dilution to label 106cells in 100ul. |
Function: |
Integrin alpha-9/beta-1 is a receptor for VCAM1 cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. |
Subunit: |
Heterodimer of an alpha and a beta subunit. Alpha-9 associates with beta-1. |
Subcellular Location: |
Membrane; Single-pass type I membrane protein. |
Tissue Specificity: |
In airway epithelium in the basal layer of squamous epithelium and in smooth muscle skeletal muscle and hepatocytes. Abundantly expressed in fetal lung and lung cancers. |
Induction: |
Up-regulated in small cell lung cancers (SCLC). |
Similarity: |
Belongs to the integrin alpha chain family. |
Similarity: |
Contains 7 FG-GAP repeats. 1. Wang. A. et al. (1996) Differential regulation of airway epithelial integrins by growth factors. 2. Smith. L. L. et al. (1996) Osteopontin N-terminal domain contains a cryptic adhesive sequence recognised by alpha9 beta1 integrin. 3. Yokosaki. Y. et al. (1996) Differential effects of the integrins alpha9 beta1. alphaV/beta3 and alphaV beta6 on cell proliferative responses to tenascin. J. Biol. Chem. 271: 24144-24150. |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.