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17-BETA-ESTRADIOL

17-BETA-ESTRADIOL


Item no.	20-783-73554
Manufacturer	GENWAY
Amount	0.2 mg
Category	Oncology Antibodies ELISA Primary Antibodies By Organ Testicular & Prostate Cancer
Type	Antibody
Applications	ELISA
Clone	4S11 (BGN/06
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-F8E548
Similar products	20-783-73554
Available
Genway ID:	GWB-F8E548
Isotype:	IgG1
Specificity:	17-BETA-ESTRADIOL. 20-783-73554 is specific for 17-beta estradiol a mammalian estrogenic hormone produced in the ovaries placenta and testis that has a role in normal sexual development and the regulation of the menstrual cycle. 20-783-73554 exhibits negligible cross reactivity with estriol and testosterone.
Specificity:	17-BETA-ESTRADIOL
Clone:	4S11 (BGN/06/8811)
Immunogen:	17-beta estradiol conjugated to bovine serum albumin at position 6.
Preparation:	Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution:	Phosphate buffered saline pH 7. 2
Preservative Stabilisers:		0. 09% Sodium Azide (NaN3)
Function:	The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1) lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
Catalytic Activity:	2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-(2-methylpropanoyl)dihydrolipoyl)lysine. Cofactor: Binds 1 lipoyl cofactor covalently.
Subunit:	Forms a 24-polypeptide structural core with octahedral symmetry.
Subcellular Location:	Mitochondrion matrix.
Disease:	Defects in DBT are the cause of maple syrup urine disease type 2 (MSUD2) [MIM:248600]. MSUD is an autosomal recessive disorder characterized by mental and physical retardation feeding problems and a maple syrup odor to the urine.
Miscellaneous:	The catalytic function of this enzyme is to accept and to transfer to coenzyme A acyl groups that are generated by the branched-chain alpha-keto acid decarboxylase component.
Similarity:	Belongs to the 2-oxoacid dehydrogenase family.
Similarity:	Contains 1 lipoyl-binding domain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.2 mg

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Delivery expected until 10/30/2025

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