Vergleich

Human Myeloma IgA1 Lambda

ArtNr 11-511-248620
Hersteller GENWAY
Menge 0.1mg
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias GWB-2FBFF6
Similar products 11-511-248620
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Genway ID:
GWB-2FBFF6
Specificity:
IgA1 lambda
Note:
IgA myeloma proteins are usually heterogeneous with respect to their molecular wieght. This preparation may contain both monomeric and polymeric forms of IgA1.
Type of Product:
Purified Human Immunoglobulins
Inactivation:
Not applicable. Preservatives: 0. 05% sodium azide
Buffer:
10mM Sodium phosphate 150mM Sodium chloride pH 7. 4Applications Notes : Specific methodologies have not been tested using this product.
Warning:
This product contains sodium azide. which has been classified as Xn (Harmful). in European Directive 67/548/EEC in the concentration range of 0. 1â ??1. 0%. When disposing of this reagent through lead or copper plumbing. flush with copious volumes of water to prevent azide build-up in drains.
Concentration:
Concentration is lot specific Human Myeloma IgA1 Lambda. Purified Human Plasma Immunoglobulin A1 (IgA1) Lambda (Monoclonal)
Function:
Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:
Monomeric or polymeric.
Ptm:
3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:
A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:
Contains 3 Ig-like (immunoglobulin-like) domains.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1mg
Lieferbar: In stock
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