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Human Myeloma IgA1 Lambda

Human Myeloma IgA1 Lambda

Item no.	11-511-248620
Manufacturer	GENWAY
Amount	0.1mg
Category	Oncology Antibodies By Cell Type Hematology Myeloma Secondary Antibodies By Organ Heart & Blood Cancer
Type	Proteins
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	GWB-2FBFF6
Similar products	11-511-248620
Available
Genway ID:	GWB-2FBFF6
Specificity:	IgA1 lambda
Note:	IgA myeloma proteins are usually heterogeneous with respect to their molecular wieght. This preparation may contain both monomeric and polymeric forms of IgA1.
Type of Product:	Purified Human Immunoglobulins
Inactivation:	Not applicable. Preservatives: 0. 05% sodium azide
Buffer:	10mM Sodium phosphate 150mM Sodium chloride pH 7. 4Applications Notes : Specific methodologies have not been tested using this product.
Warning:	This product contains sodium azide. which has been classified as Xn (Harmful). in European Directive 67/548/EEC in the concentration range of 0. 1â ??1. 0%. When disposing of this reagent through lead or copper plumbing. flush with copious volumes of water to prevent azide build-up in drains.
Concentration:	Concentration is lot specific Human Myeloma IgA1 Lambda. Purified Human Plasma Immunoglobulin A1 (IgA1) Lambda (Monoclonal)
Function:	Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:	Monomeric or polymeric.
Ptm:	3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:	A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:	Contains 3 Ig-like (immunoglobulin-like) domains.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1mg

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Delivery expected until 10/30/2025

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