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CA9 Antibody (Center)

CA9 Antibody (Center)

ArtNr	ABC-AP5000e
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IF
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CA9, G250, MN, Carbonic anhydrase 9, Carbonate dehydratase IX, Carbonic anhydrase IX, Membrane antigen MN, P54/58N, Renal cell carcinoma-associated antigen G250, pMW1, CAIX, CA-IX, RCC-associated antigen G250
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Primary Accession	Q16790
Antigen Type	Synthetic Peptide
Application	IF, FC, WB
Bio Background	Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation.
Bio References	Grabmaier, K., et al., Oncogene 23(33):5624-5631 (2004). Kaluzova, M., et al., Mol. Cell. Biol. 24(13):5757-5766 (2004). Span, P.N., et al., Br. J. Cancer 89(2):271-276 (2003). Hedley, D., et al., Clin. Cancer Res. 9(15):5666-5674 (2003). Bui, M.H., et al., Clin. Cancer Res. 9(2):802-811 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB18383
Gene ID	768
Gene Name	CA9
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Immunofluorescence analysis of CA9 Antibody (Center) with hela cells . 0.025 mg/ml primary antibody was followed by FITC-conjugated goat anti-rabbit lgG (whole molecule). FITC emits green fluorescence.
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of CA9 antibody (Center) (Cat.# AP5000e) in Hela cell line lysates (35ug/lane). CA9 (arrow) was detected using the purified Pab.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Flow cytometric analysis of hela cells using CA9 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	49698
Antigen Region	113-143
Antigen Source	HUMAN
Target/Specificity	This CA9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-143 amino acids from the Central region of human CA9.
NCBI Accession	NP_001207.2

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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