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GRB2 Antibody (Center)

GRB2 Antibody (Center)

ArtNr	ABC-AP6283C
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	GRB2, ASH, Growth factor receptor-bound protein 2, Adapter protein GRB2, SH2/SH3 adapter GRB2, Protein Ash
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Primary Accession	P62993
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences.
Bio References	Kondo, A., J. Biol. Chem. 283 (3), 1428-1436 (2008) Morimatsu, M., Proc. Natl. Acad. Sci. U.S.A. 104 (46), 18013-18018 (2007) Martinez, N., Cell. Signal. 19 (11), 2277-2285 (2007)
Clonality	Polyclonal
Clone/Animal Names	RB15648
Gene ID	2885
Gene Name	GRB2
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of GRB2 Antibody (Center) (Cat. #AP6283c) in A2058 cell line lysates (35ug/lane). GRB2 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of GRB2 (arrow) using GRB2 Antibody (Center) (Cat.#AP6283c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GRB2 gene (Lane 2) (Origene Technologies).
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human brain tissue reacted with GRB2 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~100
Other Accession	P62994; Q60631; Q6GPJ9; P87379
Predicted	X, M, Rat
Isotype	Rabbit Ig
Calculated MW	25206
Antigen Region	89-118
Antigen Source	HUMAN
Target/Specificity	This GRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the Central region of human GRB2.
NCBI Accession	NP_002077.1; NP_987102.1

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ABC-AP6283C-datasheet.pdf

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Menge: 400 ul

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