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XPO1 Antibody (C-term)

XPO1 Antibody (C-term)

ArtNr	ABC-AP6684B
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	XPO1, CRM1, Exportin-1, Chromosome region maintenance 1 protein homolog, Exp1
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Primary Accession	O14980
Antigen Type	Synthetic Peptide
Application	FC, IHC-P
Bio Background	XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
Bio References	Shen, A., Neurosurgery 65 (1), 153-159 (2009) Dong, X., Nat. Struct. Mol. Biol. 16 (5), 558-560 (2009)
Clonality	Polyclonal
Clone/Animal Names	RB19972
Gene ID	7514
Gene Name	XPO1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Formalin-fixed and paraffin-embedded human brain tissue reacted with XPO1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 1	IHC-P
Dilution image 1	1:50~100
Legend image 2	Flow cytometric analysis of widr cells using XPO1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 2	FC
Dilution image 2	1:10~50
Other Accession	Q80U96; Q6P5F9
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	123386
Antigen Region	817-846
Antigen Source	HUMAN
Target/Specificity	This XPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 817-846 amino acids from the C-terminal region of human XPO1.
NCBI Accession	NP_003391.1

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