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XPO1 Antibody (C-term)

XPO1 Antibody (C-term)

Item no.	ABC-AP6684B
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	XPO1, CRM1, Exportin-1, Chromosome region maintenance 1 protein homolog, Exp1
Available
Primary Accession	O14980
Antigen Type	Synthetic Peptide
Application	FC, IHC-P
Bio Background	XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
Bio References	Shen, A., Neurosurgery 65 (1), 153-159 (2009) Dong, X., Nat. Struct. Mol. Biol. 16 (5), 558-560 (2009)
Clonality	Polyclonal
Clone/Animal Names	RB19972
Gene ID	7514
Gene Name	XPO1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Formalin-fixed and paraffin-embedded human brain tissue reacted with XPO1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 1	IHC-P
Dilution image 1	1:50~100
Legend image 2	Flow cytometric analysis of widr cells using XPO1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 2	FC
Dilution image 2	1:10~50
Other Accession	Q80U96; Q6P5F9
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	123386
Antigen Region	817-846
Antigen Source	HUMAN
Target/Specificity	This XPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 817-846 amino acids from the C-terminal region of human XPO1.
NCBI Accession	NP_003391.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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